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The Knight- 08-25-2007
For our colleauges in the 6th grade, I wish this can be helpful for them


What is Takayasu disease?

Takayasu disease or Takayasu arteritis is a chronic inflammation of the large blood vessel that distributes blood from the heart, called the aorta. It is most common in women (90%) of Asian descent. It usually begins between 10 and 30 years of age. The cause is unknown.
Takayasu disease has also been referred to as pulseless disease and aortic arch syndrome.


What are symptoms of Takayasu disease?

The inflammation of the aorta and its branch arteries can lead to poor blood supply to tissues of the body in patients with Takayasu disease. This can cause painful, cool or blanched extremities, dizziness, headaches, chest pain, and abdominal pain. Other early symptoms can include fatigue, weight loss, and low-grade fever.


How is Takayasu disease diagnosed?

The doctor can find elevated blood pressure in over half of the patients with Takayasu disease. Abnormal sounds of blood movement through blood vessels can sometimes be heard with a stethoscope. Small notches in the ribs of the back of the chest have sometimes been detected on routine chest x- rays and are felt to be a result of abnormal pulsations of blood vessels in these areas.
The diagnosis is supported by the blood tests, such as a sedimentation rate (sed rate), that suggest inflammation in the body.
Takayasu arteritis is ultimately diagnosed with an angiogram of the arteries (arteriogram


How is Takayasu disease treated?

Takayasu disease is treated by suppressing the inflammation with cortisone medication
Examples include prednisone, prednisolone, methotrexate (Rheumatrex, Trexall), cyclosporine, cyclophosphamide (Cytoxan), and azathioprine (Imuran). Strict control of elevated blood pressure (hypertension) is important.

Good Luck fellows.


ali al-kafaji- 08-25-2007
thanks dude for this wonderful introduction

take care.

ali

lavie- 08-25-2007
thanks allot for these wonferful infos, and again the women are more
affected than the males bcmf/thmbdn.gif tongue.gif

thanks again
keep it up
cheers

Dr.Leo1984- 08-26-2007
thnx for these info.s
i want to add :
M. Takayasu is Japanese ophthalmologist (1860-1938)

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